Companies
- SpecialEffect
- Spicy Horse
- Spiders
- Spiderweb Software
- Spike Chunsoft
- Spike Co., Ltd.
- Spiral Game Studios
- Spiral House
- Splash Damage
- Sports Interactive
- Spotify
- Springfox Games
- Spry Fox
- Spyglass Entertainment
- Squanch Games
- Square Enix
- Square Enix Collective
- Square Enix Europe
- Square Enix London Mobile
- Square Enix Montréal
- Squaresoft
- Stainless Games
- Stairway Games
- Standing Stone Games
- Star Vault
- Starbreeze Studios
- Stardock
- Stardock Corporation
- Starry Studio
- Starward Industries
- State of Play
- Steamforged Games
- Steel Wool Studios
- SteelSeries
- Steve Jackson Games
- Stoic
- Stormfront Studios
- Strange Loop Games
- Strange Scaffold
- Strategy Analytics
- Strategy First
- Stray Fawn Studio
- Stress Level Zero
- Streum On Studio
- Striking Distance Studios
- Stroboskop
- Studio Drydock
- Studio Ghibli
- Studio Gobo
- Studio Liverpool