Bethesda offers Skyrim PS3 save issue workarounds
Bethesda has suggested a number of workaround tips and tricks for PlayStation 3 owners suffering memory-related issues in The Elder Scrolls V: Skyrim. Suggestions include freeing up 2GB of memory on your consoles' hard drive; disabling auto-save; and waiting or resting for up to 30 days to help clear the effects of your actions on the game world. A few advanced options using the console's safe mode are suggested too, but don't come highly recommended.
The publisher has indicated the PS3 issues are a priority and may be part of the next patch.